Compound
|
CAS#
|
---|---|
Diethyl Cyanomethylphosphonate
|
Cas# 2537-48-6
|
4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine
|
Cas#3680-69-1
|
Bromoacetaldehyde Dimethyl Acetal
|
Cas# 105-57-7
|
Bromoacetaldehyde Diethyl Acetal
|
Cas# 2032-35-1
|
Ethyl 2-Cyano-4,4-Dimethoxy Butanoate
|
Cas# 773076-83-8
|
7h-Pyrrolo(2,3-D) Pyrimidine-4-ol
|
Cas# 3680-71-5
|
4-Chloro-7h-Pyrrolo [2,3-D] Pyrimidine
|
Cas# 3680-69-1
|
2-Chloro-1,1,1-Trimethoxyethane
|
Cas# 74974-54-2
|
3-Chloropyrazine-2-Carbonitrile
|
Cas # 55557-52-3
|
15-Crown-5-Ether
|
Cas# 33100-27-5
|
Dibenzo-18-Crown-6-Ether
|
Cas# 14187-32-7
|
Benzo-15-Crown-5
|
Cas# 14098-44-3
|
18-Crown-6-Ether
|
Cas# 17455-13-9
|
4-Phenoxy Benzoic acid
|
CAS# 2215-77-2
|
3-Aminopyrazine-2-Carboxylic acid
|
CAS# 5424-01-1
|
Methyl 3-Aminopyrazine-2-Carboxylate
|
CAS# 16298-03-6
|
Methyl 3,5-Diamino-6-chloropyrazine-2-carboxylate
|
CAS# 1458-01-1
|
Diethyl Cyanomethylphosphonate
|
CAS# 2537-48-6
|
(S)-2-Aminobutane-1,4-dithiol hydrochloride
|
BIPERIDIN HYROCHLORIDE
|
BIPERIDIN LACTATE
|
BEDAQUILINE
|
BREXPIPRAZOLE
|
BRIVARACETAM
|
CLIMBAZOLE
|
DABIGATRAN ETEXILATE MESYLATE
|
DAPOXETINE
|
DABIGATRAN
|
DAPRODUSTAT
|
DIACEREIN
|
DONEPEZIL HYDROCHLORIDE
|
DOLUTEGRAVIR
|
DOSULEPIN
|
ELTROMBOPAG
|
ETODOLAC
|
IMEGLIMIN HYDROCHLORIDE
|
LULICONAZOLE
|
OXALAMINE
|
OXICONAZOLE NITRATE
|
MACITENTAN
|
MIGLUSTAT
|
NEBIVOLOL HYDROCHLORIDE
|
VODADUSTAT
|
ROXADUSTAT
|
RABEPRAZOLE
|
SITAGLIPTIN
|
TENELIGLPTIN
|
TICAGRELOR
|
TENOFOVIR ALAFENAMIDE
|
TOFACITINIB CITRATE
|
UMIFENOVIR
|
BIMATOPROST
|
CLOPROSTENOL SODIUM
|
DINOPROST
|
EPOPROSTENOL SODIUM
|
LATANOPROST
|
LUBIPROSTONE
|
MISOPROSTOL
|
TAFLUPROST
|
TRAVOPROST
|
|
|
|
BENDAMUSTINE
|
BORTEZOMIB
|
CARMUSTINE
|
IMATINIB MESYLATE
|
SORAFENIB
|
|
|
|
MISOPROSTOL | |||
---|---|---|---|
S No | Chemical Name | CAS No | Remarks |
1 | (3R)-5-Oxo-3-[(triethylsilyl)oxy]-1- cyclopentene-1 -heptanoic Acid Methyl Ester |
118456-54-5 | Misoprostol/ main chain/ Purity-NLT-95 % |
2 | (E)-triMethyl((1-iodo- 4-Methyloct-1-en-4- yl)oxy)silane |
62555-05-9 | Misoprostol/ side chain/ Purity-NLT -90% |
3 | Methyl 7-((1R,2R,3R)-3-hydroxy-2-((S,E)- 4-hydroxy-4-methyloct-1-enyl)-5- oxocyclopentyl)heptanoate |
59122-46-2 | Misoprostol Oil/ Purity-NLT -90% |
4 | Misoprostol (1% HPMC dispersion) | 103601-27-0 | 1 % Misoprostol |
BIMATOPROST | |||
---|---|---|---|
S No | Chemical Name | CAS No | Remarks |
5 | (3aR,4S,5R,6aS)-(-)-Hexahydro-5- hydroxy-4-(hydroxymethyl)-2Hcyclopenta[ b]furan-2-one |
32233-40-2 | (-) Corey lactone diol |
6 | (3aS,4R,5S,6aR)-(+)-Hexahydro-5- hydroxy-4-(hydroxymethyl)-2Hcyclopenta[ b]furan-2-one |
76704-05-7 | (+) Corey lactone diol |
7 | (3aR,4S,5R,6aS)-5-hydroxy-4- (hydroxymethyl)-3,3a,4,5,6,6ahexahydrocyclopenta[ b]furan-2-one |
54423-47-1 | (±)-Corey lactone diol |
8 | Dimethyl (2-oxo-4- phenylbutyl)phosphonate | 41162-19-0 | Bimatoprost/lower wittig |
9 | 5-(Triphenylphosphonio)pentanoic acid bromide, | 17814-85-6 | Bimatoprost/upper wittig |
10 | (3aR,4R,5R,6aS)-hexahydro-5- triethylsilane-4-((E)-3-oxo-5-phyenylpent- 1- enyl)cyclopenta[b]furan-2-one |
1190865-70-3 | Bimatoprost intermediate after lower wittig |
11 | (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2- [(1E)-3-oxo-5-phenyl-1-penten-1- yl]cyclopentyl]-N-ethyl-5-heptenamide |
1163135-96-3 | Bimatoprost 15-keto impurity |
12 | (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2- [(1E,3S)-3-hydroxy-5-phenyl-1-penten-1- yl]cyclopentyl]-5-heptenoic Acid |
38344-08-0 | Bimatoprost acid |
13 | (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2- ((E)-3-oxo-5-phenylpent-1-en-1- yl)cyclopentyl)hept-5-enamide |
155205-89-3 | Bimatoprost des ethyl impurity |
14 | methyl (Z)-7-((1R,2R,3R,5S)-3,5- dihydroxy-2-((S,E)-3-hydroxy-5- phenylpent-1-en-1-yl)cyclopentyl)hept-5- enoate |
38315-47-8 | Bimatoprost methyl ester impurity (n-1) |
15 | (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2- ((R,E)-3-hydroxy-5-phenylpent-1-en-1- yl)cyclopentyl)-N-ethylhept-5-enamide |
1163135-92-9 | Bimatoprost 15 epi impurity |
16 | (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2- ((S,E)-3-hydroxy-5-phenylpent-1-en-1- yl)cyclopentyl)-N-ethylhept-5-enamide |
155206-00-1 | Bimatoprost API |
LATANOPROST | |||
---|---|---|---|
S No | Chemical Name | CAS No | Remarks |
17 | (3aR,4R,5R,6aS)-hexahydro-5-hydroxy- 4-[(3R)-3-hydroxy-5-phenylpentyl]-2Hcyclopenta[ b]furan-2-one |
145667-75-0 | Latanoprost Lactone Diol |
18 | (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2- [(3R)-3-hydroxy-5- phenylpentyl]cyclopentyl]hept-5-enoic acid |
41639-83-2 | Latanoprost Acid |
19 | Isopropyl 4-(3-(((1R,2R,3R,5S)-3,5- dihydroxy-2-((R)-3-hydroxy-5- phenylpentyl)cyclopentyl)methyl)oxiran-2- yl)butanoate |
N/A | Latanoprost Epoxy impurity |
20 | (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2- (3-oxo-5-phenylpentyl)cyclopentyl]-5- heptenoic acid 1-methylethyl ester |
135646-98-9 | Latanoprost 15 keto impurity |
21 | Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5- dihydroxy-2-((S)-3-hydroxy-5- phenylpentyl)cyclopentyl)hept-5-enoate |
145773-22-4 | Latanoprost 15 Epi impurity |
22 | Isopropyl (Z)-7-((1R,2R,3R,5S)-5- acetoxy-3-hydroxy-2-((R)-3-hydroxy-5- phenylpentyl)cyclopentyl)hept-5-enoate |
913258-34-1 | Latanoprost Trans impurity |
23 | Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5- dihydroxy-2-((R)-3-hydroxy-5- phenylpentyl)cyclopentyl)hept-5-enoate |
130209-82-4 | Latanoprost API |
TRAVOPROST | |||
---|---|---|---|
S No | Chemical Name | CAS No | Remarks |
24 | Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5- dihydroxy-2-((S,E)-3-hydroxy-4-(3- (trifluoromethyl)phenoxy)but-1-en-1- yl)cyclopentyl)hept-5-enoate |
1420791-14-5 | Travoprost 15 epi |
25 | Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5- dihydroxy-2-((E)-3-oxo-4-(3- (trifluoromethyl)phenoxy)but-1-en-1- yl)cyclopentyl)hept-5-enoate |
404830-45-1 | Travoprost 15 keto |
26 | Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5- dihydroxy-2-((2S)-3-((S)-1-hydroxy-2-(3- (trifluoromethyl)phenoxy)ethyl)oxiran-2- yl)cyclopentyl)hept-5-enoate |
N/A | Travoprost Epoxy impurity |
27 | (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2- {(R,E)-3-hydroxy-4-[3- (trifluoromethyl)phenoxy]but-1- enyl}cyclopentyl)hept-5-enoic acid |
54276-17-4 | Travoprost Acid impurity |
28 | Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5- dihydroxy-2-((R,E)-3-hydroxy-4-(3- (trifluoromethyl)phenoxy)but-1-en-1- yl)cyclopentyl)hept-5-enoate |
157283-68-6 | Travoprost API |
29 | dimethyl (2-(3- (trifluoromethyl)phenoxy)acetyl)phospho nate |
54094-19-8 | Travoprost Side chain |
CLOPROSTENOL | |||
---|---|---|---|
S No | Chemical Name | CAS No | Remarks |
30 | 15-epi Cloprostenol/(5Z)-7- [(1R,2R,3R,5S)-2-[(1E,3R)-4-(3- Chlorophenoxy)-3-hydroxy-1-buten-1-yl]- 3,5-dihydroxycyclopentyl]-5-heptenoic acid |
54276-22-1 | (+)-15(S)-CLOPROSTENOL |
31 | [1R- [1alpha(E),2beta(1E,3R*),3alpha,5alpha] ]-7-[2-[4-(3-Chlorophenoxy)-3-hydroxy-1- butenyl]-3,5-dihydroxycyclopentyl]-5- Heptenoic acid |
57968-81-7 | (+)-trans Cloprostenol |
32 | (5Z)-7-{(1R,2R,3S,5S)-2-[(1E)-4-(3- chlorophenoxy)-3-hydroxybut-1-en-1-yl]- 3,5-dihydroxycyclopentyl}hept-5-enoic acid |
40665-93-8 | 15S-(+/-)-Cloprostenol |
33 | (5Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3- chlorophenoxy)-3-hydroxy-1-buten-1-yl]- 3,5-dihydroxycyclopentyl]-5-heptenoic acid sodium |
55028-72-3 | Cloprostenol Sodium API |
34 | dimethyl (2-(3- chlorophenoxy)acetyl)phosphonate |
40665-94-9 | Cloprostenol Side chain |
CRABOPROST | |||
---|---|---|---|
S No | Chemical Name | CAS No | Remarks |
35 | DIMETHYL (2- OXOHEPTYL)PHOSPHONATE | 36969-89-8 | Carboprost side chain |
36 | (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2- ((S,E)-3-hydroxy-3-methyloct-1-en-1- yl)cyclopentyl)hept-5-enoic Acid |
35700-23-3 | Carboprost Acid |
37 | Methyl (E)-7-[(1S,3S,5R)-3,5-dihydroxy- 2-[(Z,3S)-3-hydroxy-3-methyloct-1- enyl]cyclopentyl]hept-5-enoate |
35700-21-1 | Carboprost Methyl Ester |
38 | (5Z)-7- [ (1R,2R,3R,5S)-3,5-Dihydroxy-2- [ (1E,3R)-3-hydroxy-3-methyloct-1- enyl]cyclopentyl]hept-5-enoic Acid |
35864-81-4 | Carboprost 15 epi |
39 | (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy- 15- methylprosta-5,13-dien-1-oic acid with 2-amino-2-(hydroxymethyl)-1,3- propanediol |
58551-69-2 | Carboprost Tromethamine |
TAFLUPROST | |||
---|---|---|---|
S No | Chemical Name | CAS No | Remarks |
40 | Dimethyl(2-oxo-3- phenoxypropyl)phosphonate | 40665-68-7 | Tafluprost \ side chain |
41 | (3aR,4R,5R,6aS)-4-[(1E)-3,3-Difluoro-4- phenoxy-1-butenyl]hexahydro-5-hydroxy- 2H-cyclopenta[b]furan-2-one |
209861-01-8 | Tafluprost \ HF |
42 | (3aR,4R,5R,6aS)-;(3AR,4R,5R,6aS)-4- ((E)-3,3-Difluoro-4-phenoxybut-1-en-1- yl)-2-oxohexahydro-2Hcyclopenta[ b]furan |
209861-00-7 | Tafluprost \ BF |
43 | 7-[2-(3,3-difluoro-4-phenoxybut-1-enyl)- 3,5-dihydroxycyclopentyl]hept-5-enoic acid |
209860-88-8 | Tafluprost \ Acid |
44 | 7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-
phenoxy-1-buten-1-yl]-3,5- dihydroxycyclopentyl]-,1-methylethyl ester |
209860-87-7 | Tafluprost \ API |
DINOPROST | |||
---|---|---|---|
S No | Chemical Name | CAS No | Remarks |
45 | Dimethyl(2-oxo-3- phenoxypropyl)phosphonate |
551-11-1 | Dinoprost acid |
46 | (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2- [(E)-(3R)-3-hydroxyoct-1- enyl]cyclopentyl]hept-5-enoic Acid |
37658-84-7 | dinoprost 15 epimer |
47 | (5Z,9S,11S,13E,15S)-9,11,15- Trihydroxyprosta-5,13-dien-1-oic acid methyl ester |
33854-16-9 | Dinoprost methyl ester |
48 | (5Z,9α,11α,13E,15S)-9,11,15- Trihydroxyprosta-5,13-dienoic acid tris salt |
38562-01-5 | Dinoprost tromethamine (API) |
49 | (3AR,4R,5R,6aS)-5-Hydroxy-4-((S,E)-3- hydroxyoct-1-en-1-yl)hexahydro-2Hcyclopenta[ b]furan-2-one |
26054-67-1 | Dinoprost intermediate |
DINOPROSTONE | |||
---|---|---|---|
S No | Chemical Name | CAS No | Remarks |
50 | 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5- oxocyclopentyl)-5- heptenoicaci;dinoproston |
363-24-6 | Dinoprostone API |
51 | (Z)-7-[(1S,2R,3R)-3-hydroxy-5-oxo-2- [(E)-3-oxooct-1-enyl]cyclopentyl]hept-5- enoic acid |
914804-63-0 | Dinoprostone Keto impurity |
52 | (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E)-(3R)- 3-hydroxyoct-1-enyl]-5- oxocyclopentyl]hept-5-enoic acid |
38873-82-4 | Dinoprostone epimer impurity |
53 | Z)-7-[(1S,2R,3R)-3-hydroxy-2-[(E,3S)-3- hydroxyoct-1-enyl]-5- oxocyclopentyl]hept-5-enoic acid |
27415-25-4 | Dinoprostone Acid |
TREPROSTINIL | |||
---|---|---|---|
S No | Chemical Name | CAS No | Remarks |
54 | 1H-Benz[f]inden-2-ol, 2,3,3a,4,9,9ahexahydro- 1-[(1E,3S)-3-hydroxy-1-octen- 1-yl]-5-methoxy-, (1R,2R,3aS,9aS) |
1903779-33-8 | Treprostinil / advanced intermediates |
55 | 1H-Benz[f]indene-2,5-diol, 2,3,3a,4,9,9ahexahydro-1-[(1E,3S)-3- hydroxy 1-octen1-yl]-, 5- |
1425937-55-8 | Treprostinil / advanced intermediates |
56 | 1H-Benz[f]indene-2,5-diol, 2,3,3a,4,9,9ahexahydro-1-[(1E,3S)-3- hydroxy 1-octen1-yl]-, |
1257983-83-7 | Treprostinil / advanced intermediates |
57 | Acetonitrile, 2- [[(1R,2R,3aS,9aS)2,3,3a,4,9,9a-hexahydro-2- hydroxy-1- [(1E,3S)-3-hydroxy-1-octen-1-yl]- 1Hbenz[f]inden-5-yl]oxy] |
1425937-57-0 | Treprostinil / advanced intermediates |
58 | Acetic acid, [[2,3,3a,4,9,9a-hexahydro- 2hydroxy-1-(3-hydroxy-1-octenyl)- 1Hbenz[f]inden-5-yl]oxy]-, [1R- [1α(1E,3S*),2β,3aα,9aα]] |
81845-88-7 | Treprostinil / advanced intermediates |
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